Synthetic biology involves the creation of biological systems for new applications by modifying and reassembling biological components. Two views are presented here on the best way to engineer these components so that they reliably generate organisms with desired traits.
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References
Gardner, T. S., Cantor, C. R. & Collins, J. J. Nature 403, 339–342 (2000).
Kotula, J. W. et al. Proc. Natl Acad. Sci. USA http://dx.doi.org/10.1073/pnas.1321321111 (2014).
Keasling, J. D. Proc. Am. Phil. Soc. 156, 283–294 (2012).
Sarkar, I., Hauber, I., Hauber, J. & Buchholz, F. Science 316, 1912–1915 (2007).
Bastian, S. et al. Metab. Eng. 13, 345–352 (2011).
Romero, P. A. & Arnold, F. H. Nature Rev. Mol. Cell Biol. 10, 866–876 (2009).
Trudeau, D. L., Smith, M. A. & Arnold, F. H. Curr. Opin. Chem. Biol. 17, 902–909 (2013).
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Silver, P., Way, J., Arnold, F. et al. Engineering explored. Nature 509, 166–167 (2014). https://doi.org/10.1038/509166a
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DOI: https://doi.org/10.1038/509166a
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