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Drug discovery goes au naturel

A Correction to this article was published on 16 April 2014

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In a study that showcases the potential of semisynthetic drug design, structural modification of an existing antibiotic with little activity against Mycobacterium tuberculosis has generated a new class of effective antitubercular lead.

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Figure 1: Natural complexity.

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Correspondence to Clifton E. Barry.

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Barry, C. Drug discovery goes au naturel. Nature 506, 436–437 (2014).

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