The discovery that most CD4+ T cells killed during HIV infection die through a process known as pyroptosis may provide long-sought explanations for HIV-associated T-cell depletion and inflammation. See Article p.509
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Cox, A., Siliciano, R. Not-so-innocent bystanders. Nature 505, 492–493 (2014). https://doi.org/10.1038/505492a
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DOI: https://doi.org/10.1038/505492a
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