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Stem cells

Sex specificity in the blood

Haematopoietic stem cells, from which blood cells originate, are shown to respond to oestrogen and divide more frequently in female mice than in males, probably preparing females for the increased demand for blood in pregnancy. See Letter p.555

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Figure 1: Oestrogen regulates stem-cell cycling.


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Correspondence to Anne Brunet.

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Leeman, D., Brunet, A. Sex specificity in the blood. Nature 505, 488–489 (2014).

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