Ketolide antibiotics have been found to induce a ribosomal frameshift — a change in the way that RNA is translated — in bacteria. This promotes the expression of a gene for antibiotic resistance, and may have broader implications.
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Atkins, J., Baranov, P. Antibiotic re-frames decoding. Nature 503, 478–479 (2013). https://doi.org/10.1038/503478a
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