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Physiology

A metabolic minuet

Nature volume 502, pages 454–455 (2013)Cite this article

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Two related nuclear receptors mediate circadian fat metabolism in two different tissues using a lipid messenger as an intermediary. This signalling pathway might be relevant to the understanding of metabolic disorders. See Letter p.550

In the minuet, a popular court dance of the baroque era, couples exchange partners in recurring patterns. This elaborately choreographed exercise comes to mind when reading Liu and colleagues' paper1 on page 550 of this issue. In this study, the nuclear receptors PPARα and PPARδ are two of the three stars in a metabolic minuet that promotes appropriate fat utilization.

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Figure 1: Cross-tissue regulation of fat metabolism.

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  1. David D. Moore is in the Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.,

    David D. Moore

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  1. David D. Moore
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Correspondence to David D. Moore.

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Moore, D. A metabolic minuet. Nature 502, 454–455 (2013). https://doi.org/10.1038/502454a

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