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Calculated treatment

Mathematical modelling linked with patient data suggests that combination therapy is more effective than sequential treatment at preventing drug resistance in cancer. This predictive approach may pave the way for personalized therapies.

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Figure 1: Single-drug versus combination therapy.


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Correspondence to Natalia L. Komarova.

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Komarova, N., Boland, C. Calculated treatment. Nature 499, 291–292 (2013).

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