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US research firms put under pressure to sell

Commercialization rules threaten to curtail SBIR grants.

Equipment made by Creare, an SBIR grant recipient, is loaded into the Mars Science Laboratory rover. Credit: NASA

The offices of Physical Sciences Inc. (PSI), a small scientific research company in Andover, Massachusetts, feel not too dissimilar from a technical university. The brick and glass building boasts an atomic oxygen chamber for testing how new materials act in outer space, as well as a next-generation ophthalmic device that makes high-resolution maps of the retina. Chief executive Dave Green looks like an academic as he hangs out in the atrium wearing a baseball cap; the only sign that he operates a for-profit business is the shirt and tie that hide beneath his zip-up sweater.

PSI, in fact, is not much of a commercial operation. Most of its revenue comes from research performed for larger companies and the government, and nearly one-third of it, US$10.5 million, comes directly from a single federal source: the US Small Business Innovation Research (SBIR) programme. According to guidance from the Small Business Administration, which oversees the programme, the grants are supposed to lead to commercial activity and are not merely to fund long-term research operations. However, an analysis by Nature of government data suggests that the top award winners are research-focused companies such as PSI that do not sell products, and many companies depend on SBIR funding, year after year, for a large part of their revenue stream (see ‘Small business, big awards’).

That era may be about to end.


The SBIR programme is based on the requirement that government agencies set aside 2.7% of their research budgets, about $2 billion per year in total, for grants to small businesses. In 2011, Congress reauthorized it for another five years but added requirements that the Small Business Administration track the outcomes of the grants. To facilitate this, the administration issued policy guidelines last year requiring agencies to monitor commercialization more closely. A set of benchmarks for doing so were due out on 1 July, although they have been delayed owing to employee turnover, according to a Small Business Administration spokesman.

If the benchmarks have any teeth to them, companies such as PSI, which has never brought a product to market in its 30-year history of winning SBIR awards, will struggle. “The explicit commercial side of it, if it’s really enforced, is going to cause problems for companies like us,” says Greg Zacharias of Charles River Analytics, a research and development company in Cambridge, Massachusetts, that won 44 SBIR awards worth a total of $8.8 million in 2011.

It is not as if these research and development firms are unproductive. With a history of SBIR awards going back two decades, PSI has flown an instrument on the space shuttle to study gas release and ionization, put a fuel-quality monitor into a US Navy aircraft carrier and developed a helicopter-like device for the US Department of Defense that is the size of a human hand and can fly a reconnaissance camera at up to 89 kilometres per hour.

The problem with asking agencies to measure commercialization, says Green, is that it can take many forms besides selling on the open market. To him, commercialization also includes selling prototypes to the government agencies that initially funded their development, filing and licensing patents, and spinning off technologies — something PSI did with an earlier generation of the ophthalmic device, which is now being sold to hospitals. Although the effect of the new reporting requirements and benchmarks has yet to be seen, some SBIR-supported scientists fear that the changes will strongly favour companies that bring products to market, an approach that is at odds with PSI’s business model. “Our goal is not necessarily that we build a product,” says Green, “but that someone builds it.”

Justifying the research focus of certain SBIR companies has always been tough. Some critics call the companies ‘mills’, a pejorative reference to the number of grant applications they crank out each year. About 1% of companies receiving SBIR support get 13% of the funds, according to Nature’s analysis. The top award holder in 2011 was Physical Optics Corporation in Torrance, California, which specializes in integrating components into working systems, such as data recorders for the Navy’s T-45 aircraft. In 2011 it won 94 awards worth $32 million, which made up 63% of its annual revenue of $51 million. Company spokesman Rick Shie says that these numbers are not the whole story: Physical Optics has a strong commercial side that since 1985 has shipped products worth more than $200 million. However, there is little doubt that it and others retain a strong research focus. “The mills exist,” says Zoltan Acs, an expert on entrepreneurship at George Mason University in Fairfax, Virginia, who used to work at the Small Business Administration. “If you want to defend the system, you have to defend the mills.”

“ Our goal is not necessarily that we build a product, but that someone builds it. ”

The companies argue that they are using government dollars to fulfil crucial US research needs, even if they are not pioneering consumer products. For example, the company that won the second-largest slice of grant money in 2011 — Creare in Hanover, New Hampshire — has provided important equipment to NASA. It developed vacuum pumps for a sample-analysis instrument on the Curiosity Mars rover and built cooling systems for the Hubble Space Telescope. However, the market for such technology will always be small because of the limited number of space missions and the unique nature of components such as the Hubble cooling system. “It was a one-off, but it was fantastic,” says Charles Wessner, a policy expert at the US National Academy of Sciences in Washington DC who commends the SBIR programme.

Charles River Analytics has a few non-government clients, although it specializes in developing command and control software for the military. Zacharias says the last time his company sold a commercial product was in the 1990s, when a website personalization tool it developed was sold to another company that in turn sold it to the software developer Adobe. “If someone asked us what was the commercial output of that, it would take a bunch of forensic accountants,” he says.

How exactly commercialization should be measured will become clearer when government agencies define their commercialization benchmarks, but Matthew Portnoy, programme coordinator for the SBIR at the National Institutes of Health, says the principle behind them will be clear. “We’re always interested in a product ultimately getting to market,” he says. Although programme managers have been working to measure commercial success in a nuanced way, they do have to honour Congress’s apparent desire to shift the programme’s direction away from research, he adds.

When the SBIR programme was conceived in 1982, fulfilling governmental research needs was seen as an end in itself, and a goal that could exist alongside the commercialization of products. And agencies have always preferred to steer money to their own priorities, says Ann Eskesen, a technology-transfer expert in Swampscott, Massachusetts. The real value of SBIR companies, she says, is as a reservoir of distributed research and development that can serve US business. With the decline of research and development laboratories at corporations, larger firms that have sudden scientific need often buy up several SBIR companies to solve their research problems. Her tally of SBIR acquisitions shows that General Electric has bought 12 SBIR-supported companies, defence giant Lockheed Martin has bought 10 and biotechnology company Genzyme has bought 6.

PSI is unlikely to be bought, says Green, although he says that the company will continue to try to spin off technologies. Still, he likes the analogy to a corporate research and development department. The difference is that in many companies, product commercialization makes the researchers who did the work redundant. At PSI, when work is spun off or licensed, researchers stay on the payroll and turn to a new research problem — and a new SBIR award. “We’re a research company and proud of it,” he says. “Researchers don’t get along in product companies.”

Table 7.11379 Small business, big awards

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Samuel Reich, E. US research firms put under pressure to sell. Nature 499, 137–138 (2013).

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