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Structural biology

Signalling from disordered proteins

The discovery that a disordered protein can transmit signals between two binding sites calls into question the idea that communication within proteins requires a specific structural pathway linking such sites. See Letter p.390

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Figure 1: The structural view of allostery.
Figure 2: The ensemble view of allostery.

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Correspondence to Vincent J. Hilser.

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Hilser, V. Signalling from disordered proteins. Nature 498, 308–310 (2013). https://doi.org/10.1038/498308a

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