Educating patients is key, but the US National Cancer Institute must keep spending in check.
Cancer experts from 15 countries last week published their reckoning of what it would take to combat the disease on a global scale. They highlighted the need for action and the scale of the problem — 12.7 million new diagnoses a year, more than half of them in developing nations — then ticked off a laundry list of developments needed to drive down that number, and to improve care for people with cancer.
It is an ambitious set of goals. From internationally agreed standards for preclinical animal models to harmonized clinical-trial protocols, the report lays out a framework that will require resources and coordination on an unprecedented scale (H. Varmus and H. S. Kumar Sci. Transl. Med. 5, 175cm2; 2013).
The problem needs focus, and all involved must pull in the same direction. Yet last November, the same month that the cancer experts signed off on their recommendations, the US National Cancer Institute (NCI) resurrected a subcommittee of its advisory board to get to grips with a more local problem: the US$381.2 million that it had spent on its Office of Communications and Education (OCE) between 2006 and 2012.
The figure is high enough to make even bureaucratically hardened Washington DC insiders gasp. On 1 March, the respected cancer-research bulletin The Cancer Letter pointed out that the OCE’s 2012 budget of nearly $45 million was almost double what the US Food and Drug Administration spent on communications, including drug and food safety announcements (P. Goldberg The Cancer Letter 39, 9; 2013).
The news comes at an already troubling time for US cancer research. Funding agencies must strip 5% from their spending as part of budgetary sequestration, a failed political ploy to force lawmakers to trim the national budget. Where that will leave cancer research is still unclear: little information has trickled out to the public about how and where the cuts will be made. But the NCI’s success rate for grant applications was already at 14%, an all-time low. At a press conference last September, director Harold Varmus predicted that the rate would fall even lower if sequestration were to take effect.
The OCE produces educational brochures for cancer patients and doctors, and runs Physician Data Query, a comprehensive database that includes clinical-trial summaries and definitions of medical terms. It also updates the NCI’s websites, runs a hotline for patients and arranges the institute’s exhibits at conferences.
In 2007, an external consultancy determined that the office had fallen prey to ‘mission creep’, losing its focus as a parade of directors shifted course repeatedly over the previous 10 years. Lack of focus, it seems, bred a behemoth. Whatever the cause of the largesse that allowed the OCE’s bloated budget, it will only encourage lawmakers determined to slash access to public funds. And it is galling for those researchers who are scrambling to keep their labs alive. As The Cancer Letter has pointed out, the OCE’s 2012 allotment would cover more than 100 coveted R01 research grants (P. Goldberg The Cancer Letter 38, 45; 2012).
With the revival of its advisory board’s subcommittee on communications, the NCI has an opportunity to end the mission creep, focus efforts and reduce its budget. This is not the first time that Varmus has had to trim the fat from NCI programmes. He successfully tackled the cancer Biomedical Informatics Grid, which came under fire in 2011 when NCI advisers questioned its $350-million price tag. And the institute has already taken steps to rein in the OCE’s budget: its 2012 allotment, although large, reflected a 34% cut from 2006, when the office’s spending topped $68 million. The subcommittee is next scheduled to present at an advisory board meeting in June.
There is no doubt that education of patients is crucial for cancer care and for clinical-trial recruitment. But the institute can surely continue to educate while tightening its belt, perhaps by consolidating the OCE’s other administrative tasks. It must evaluate outside contracts and consider partnering with philanthropic groups to produce educational materials. In an era of ambitious goals and shrinking resources, that could free up much-needed money for research.
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Cancer costs. Nature 495, 142 (2013). https://doi.org/10.1038/495142a
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