Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News Feature
  • Published:

Reproductive biology: Fertile mind

Jonathan Tilly defied decades of dogma by suggesting that women can make new eggs throughout their lives. Now some of his critics are taking a second look.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Johnson, J. et al. Nature 428, 145–150 (2004).

    Article  ADS  CAS  Google Scholar 

  2. White, Y. A. R. et al. Nature Med. 18, 413–421 (2012).

    Article  CAS  Google Scholar 

  3. Zuckerman, S. Recent Prog. Horm. Res. 6, 63–109 (1951).

    Google Scholar 

  4. Gosden, R. G. Hum. Reprod. Update 10, 193–195 (2004).

    Article  Google Scholar 

  5. Johnson, J. et al. Cell 122, 303–315 (2005).

    Article  CAS  Google Scholar 

  6. Telfer, E. E. et al. Cell 122, 821–822 (2005).

    Article  CAS  Google Scholar 

  7. Eggan, K. et al. Nature 441, 1109–1114 (2006).

    Article  ADS  CAS  Google Scholar 

  8. Lee, H. J. et al. J. Clin. Oncol. 25, 3198–3204 (2007).

    Article  CAS  Google Scholar 

  9. Zou, K. et al. Nature Cell Biol. 11, 631–636 (2009).

    Article  CAS  Google Scholar 

  10. Tilly, J. L. & Telfer, E. E. Mol. Hum. Reprod. 15, 393–398 (2009).

    Article  Google Scholar 

  11. Zhang, H. et al. Proc. Natl Acad. Sci. USA 109, 12580–12585 (2012).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Related video

Related links

Related links

Related links in Nature Research

Mouse stem cells lay eggs 2012-Oct-04

Egg-making stem cells found in adult ovaries 2012-Feb-27

Ageing: Much ado about ageing 2010-Mar-24

Making new eggs in old mice 2009-Apr-11

Born or made? Debate on mouse eggs reignites 2006-Jun-14

Ovaries may lay new eggs 2004-Mar-11

Related external links

Jonathan Tilly

OvaScience

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gura, T. Reproductive biology: Fertile mind. Nature 491, 318–320 (2012). https://doi.org/10.1038/491318a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/491318a

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing