Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Immunology

Tolerating pregnancy

Nature volume 490, pages 47–48 (2012)Cite this article

Subjects

The activity of specific suppressive immune cells, some of which persist to aid subsequent pregnancies, helps to explain how a pregnant female's immune system tolerates fetal antigens inherited from the father. See Letter p.102

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Immune memory for a father's antigens.

References

  1. Rowe, J., Ertelt, J., Xin, L. & Way, S. S. Nature 490, 102–106 (2012).

    Article  ADS  CAS  Google Scholar 

  2. Sasaki, Y. Mol. Hum. Reprod. 10, 347–353 (2004).

    Article  CAS  Google Scholar 

  3. Tafuri, A., Alferink, J., Möller, P., Hämmerling, G. J. & Arnold, B. Science 270, 630–633 (1995).

    Article  ADS  CAS  Google Scholar 

  4. Aluvihare, V. R., Kallikourdis, M. & Betz, A. G. Nature Immunol. 5, 266–271 (2004).

    Article  CAS  Google Scholar 

  5. Sakaguchi, S., Miyara, M., Costantino, C. M. & Hafler, D. A. Nature Rev. Immunol. 10, 490–500 (2010).

    Article  CAS  Google Scholar 

  6. Andersen, K. G., Nissen, J. K. & Betz, A. G. Front. Immunol. 3, 113 (2012).

    Article  CAS  Google Scholar 

  7. Samstein, R. M., Josefowicz, S. Z., Arvey, A., Treuting, P. M. & Rudensky, A. Y. Cell 150, 29–38 (2012).

    Article  CAS  Google Scholar 

  8. Rosenblum, M. D. et al. Nature 480, 538–542 (2011).

    Article  ADS  CAS  Google Scholar 

  9. Munoz-Suano, A., Kallikourdis, M., Sarris, M. & Betz, A. G. J. Autoimmunity 38, J103–J108 (2012).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Alexander G. Betz is at the MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, UK.,

    Alexander G. Betz

Authors
  1. Alexander G. Betz
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Alexander G. Betz.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Betz, A. Tolerating pregnancy. Nature 490, 47–48 (2012). https://doi.org/10.1038/490047a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/490047a

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing