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Organic synthesis

A biochemical messenger made easily

Biochemicals known as prostaglandins are challenging targets for synthetic organic chemistry. Yet by channelling the reactivity of a simple reactant, a powerful synthesis of one such compound has been achieved. See Letter p.278

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Figure 1: Landmark syntheses of prostaglandin F (PGF).
Figure 2: A concise synthesis of PGF.


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Correspondence to Erik J. Sorensen.

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Sorensen, E. A biochemical messenger made easily. Nature 489, 214–215 (2012).

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