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Structural biology

A protein engagement RING

Nature volume 489, pages 43–44 (2012)Cite this article

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The mechanistic details of the attachment of a small protein, ubiquitin, to other proteins are unclear. Crystal structures of the complexes formed by the E2–ubiquitin and RING E3 enzymes offer new insights. See Article p.115

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Figure 1: A unified model for ubiquitin transfer.

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Authors and Affiliations

  1. Christopher D. Lima is in the Structural Biology Program, Sloan-Kettering Institute, New York, New York 10065, USA.,

    Christopher D. Lima

  2. Department of Structural Biology, Brenda A. Schulman is at the Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.,

    Brenda A. Schulman

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  1. Christopher D. Lima
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  2. Brenda A. Schulman
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Correspondence to Christopher D. Lima or Brenda A. Schulman.

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Lima, C., Schulman, B. A protein engagement RING. Nature 489, 43–44 (2012). https://doi.org/10.1038/489043a

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