Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Tissue engineering

Blood vessels on a chip

To understand how blood vessels form and function, scientists require reproducible systems that mimic living tissues. An innovative approach based on microfabricated vessels provides a key step towards this goal.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Figure 1: In vitro microvessels.


  1. Carmeliet, P. Nature 438, 932–936 (2005).

    ADS  CAS  Article  Google Scholar 

  2. Zheng, Y. et al. Proc. Natl Acad. Sci. USA 109, 9342–9347 (2012).

    ADS  CAS  Article  Google Scholar 

  3. van der Meer, A. D., Poot, A. A., Duits, M. H., Feijen, J. & Vermes, I. J. Biomed. Biotechnol. 2009, 8231–8248 (2009).

    Article  Google Scholar 

  4. Potente, M., Gerhardt, H. & Carmeliet, P. Cell 146, 873–887 (2011).

    CAS  Article  Google Scholar 

  5. Price, G. M. et al. Biomaterials 31, 6182–6189 (2010).

    CAS  Article  Google Scholar 

  6. Tsai, M. et al. J. Clin. Invest. 122, 408–418 (2012).

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Holger Gerhardt.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Franco, C., Gerhardt, H. Blood vessels on a chip. Nature 488, 465–466 (2012).

Download citation

  • Published:

  • Issue Date:

  • DOI:

Further reading


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing