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Structural biology

Dynamic binding

Nuclear magnetic resonance spectroscopy has been used to establish a vital role for protein motion in the formation of a protein–DNA complex. The finding potentially opens up fresh approaches for modifying protein function. See Letter p.236

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Figure 1: Conformational entropy can modulate protein–DNA binding.

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Correspondence to Lewis E. Kay.

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Baldwin, A., Kay, L. Dynamic binding. Nature 488, 165–166 (2012). https://doi.org/10.1038/488165a

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