A smile would have crossed the late Andrew Huxley's face at your description of his “experiments on the axon of the giant squid” (Nature 486, 10–11; 2012). Huxley was giant, the axon was giant, but the squid were quite average in size.
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Horton, J. Giants all around — apart from the squid. Nature 488, 32 (2012). https://doi.org/10.1038/488032e