Controlling the positions at which chemical groups attach to benzene rings is vital for the synthesis of materials and medicines. A reaction that targets a normally inaccessible position takes chemists closer to this goal. See Letter p.518
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References
Benfey, O. T. J. Chem. Educ. 35, 21–23 (1958).
Leow, D., Li, G., Mei, T.-S. & Yu, J.-Q. Nature 486, 518–522 (2012).
Makosza, M. Synthesis 15, 2341–2356 (2011).
Snieckus, V. Chem. Rev. 90, 879–933 (1990).
Macklin, T. & Snieckus, V. in Handbook of C–H Transformations (ed. Dyker, G.) 106–119 (Wiley-VCH, 2005).
Chen, X., Engle, K. M., Wang, D.-H. & Yu, J.-Q. Angew. Chem. Int. Edn 48, 5094–5115 (2009).
Mills, R. J., Taylor, N. J. & Snieckus, V. J. Org. Chem. 54, 4372–4385 (1989).
Akai, S., Peat, A. J. & Buchwald, S. L. J. Am. Chem. Soc. 120, 9119–9125 (1998).
Mkhalid, I. A. I., Barnard, J. H., Marder, T. B., Murphy, J. M. & Hartwig, J. F. Chem. Rev. 110, 890–931 (2010).
Andrikopoulos, P. C. et al. Angew. Chem. Int. Edn 44, 3459–3462 (2005).
Phipps, R. J. & Gaunt, M. J. Science 323, 1593–1597 (2009).
Duong, H. A., Gilligan, R. E., Cooke, M. L., Phipps, R. J. & Gaunt, M. J. Angew. Chem. Int. Edn 50, 463–466 (2011).
Schwarz, H. Acc. Chem. Res. 22, 282–287 (1989).
Rousseau, G. & Breit, B. Angew. Chem. Int. Edn 50, 2450–2494 (2011).
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Kitching, M., Snieckus, V. Directors extend their reach. Nature 486, 478–479 (2012). https://doi.org/10.1038/486478a
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DOI: https://doi.org/10.1038/486478a
