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Nanotechnology

The importance of being modular

DNA is the material of choice for making custom-designed, nanoscale shapes and patterns through self-assembly. A new technique revisits old ideas to enable the rapid prototyping of more than 100 such DNA shapes. See Letter p.623

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References

  1. Wei, B., Dai, M. & Yin, P. Nature 485, 623–626 (2012).

    Article  CAS  ADS  Google Scholar 

  2. Seeman, N. C. J. Theor. Biol. 99, 237–247 (1982).

    Article  CAS  Google Scholar 

  3. Chen, J. & Seeman, N. C. Nature 350, 631–633 (1991).

    Article  CAS  ADS  Google Scholar 

  4. Rothemund, P. W. K. Nature 440, 297–302 (2006).

    Article  CAS  ADS  Google Scholar 

  5. Andersen, E. S. et al. Nature 459, 73–76 (2009).

    Article  CAS  ADS  Google Scholar 

  6. Douglas, S. M. et al. Nature 459, 414–418 (2009).

    Article  CAS  ADS  Google Scholar 

  7. Dietz, H., Douglas, S. M. & Shih, W. M. Science 325, 725–730 (2009).

    Article  CAS  ADS  Google Scholar 

  8. Han, D. et al. Science 332, 342–346 (2011).

    Article  CAS  ADS  Google Scholar 

  9. Maune, H. T. et al. Nature Nanotechnol. 5, 61–66 (2010).

    Article  CAS  ADS  Google Scholar 

  10. Endo, M., Katsuda, Y., Hidaka., K. & Sugiyama, H. Angew. Chem. Int. Edn 49, 9412–9416 (2010).

    Article  CAS  Google Scholar 

  11. Douglas, S. M. et al. Science 335, 831–834 (2012).

    Article  CAS  ADS  Google Scholar 

  12. Winfree, E., Liu, F., Wenzler, L. A. & Seeman, N. C. Nature 394, 539–544 (1998).

    Article  CAS  ADS  Google Scholar 

  13. Rothemund, P. W. K. & Winfree, E. Proc. 32nd Annu. Symp. Theor. Comput. 459–468 (2000).

  14. Andersen, E. S. et al. ACS Nano 2, 1213–1218 (2008).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Paul W. K. Rothemund or Ebbe Sloth Andersen.

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Competing interests

P.W.K.R. is the inventor on a patent that describes the method of ‘scaffolded DNA origami’. For certain nanopatterning applications, the method in the paper described by Yin et al. is a competitor with the method of DNA origami.

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Rothemund, P., Andersen, E. The importance of being modular. Nature 485, 584–585 (2012). https://doi.org/10.1038/485584a

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