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Microfluidics

Analog-to-digital drug screening

Current methods for screening libraries of compounds for biological activity are rather cumbersome, slow and imprecise. A method that breaks up a continuous flow of a compound's solution into droplets offers radical improvements.

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Figure 1: High-resolution dose–response screening.

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Correspondence to Robert C. R. Wootton or Andrew J. deMello.

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Wootton, R., deMello, A. Analog-to-digital drug screening. Nature 483, 43–44 (2012). https://doi.org/10.1038/483043a

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