Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Materials science

Cell environments programmed with light

A combination of two light-induced reactions has been used to attach peptides to a polymeric gel, and then to detach them from it. This feat opens up opportunities for studying the effects of signalling molecules on cell behaviour in vitro.

Your institute does not have access to this article

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Reversible gel patterning.

References

  1. Fenno, L., Yizhar, O. & Deisseroth, K. Annu. Rev. Neurosci. 34, 389–412 (2011).

    CAS  Article  Google Scholar 

  2. DeForest, C. A. & Anseth, K. S. Angew. Chem. Int. Edn 51, 1816–1819 (2012).

    CAS  Article  Google Scholar 

  3. Morrison, S. J. & Spradling, A. C. Cell 132, 598–611 (2008).

    CAS  Article  Google Scholar 

  4. Sato, T. et al. Nature 459, 262–265 (2009).

    ADS  CAS  Article  Google Scholar 

  5. Khetan, S. & Burdick, J. A. Soft Matter 7, 830–838 (2011).

    ADS  CAS  Article  Google Scholar 

  6. Kloxin, A. M., Kasko, A. M., Salinas, C. N. & Anseth, K. S. Science 324, 59–63 (2009).

    ADS  CAS  Article  Google Scholar 

  7. Khetan, S. & Burdick, J. A. Biomaterials 31, 8228–8234 (2010).

    CAS  Article  Google Scholar 

  8. Hahn, M. S., Miller, J. S. & West, J. L. Adv. Mater. 18, 2679–2684 (2006).

    CAS  Article  Google Scholar 

  9. Wylie, R. G. et al. Nature Mater. 10, 799–806 (2011).

    ADS  CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Matthias P. Lutolf.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Lutolf, M. Cell environments programmed with light. Nature 482, 477–478 (2012). https://doi.org/10.1038/482477a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/482477a

Further reading

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing