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Cell biology

Destruction deconstructed

Correctly dismantling a structure can be as challenging as assembling it. The architecture of the yeast proteasome reveals this enzyme's intricate machinery for protein degradation. See Article p.186

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Figure 1: The evolution of proteases.
Figure 2: Subunit architecture of the yeast proteasome regulatory particle1.

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Correspondence to Daniel Finley.

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Tian, G., Finley, D. Destruction deconstructed. Nature 482, 170–171 (2012). https://doi.org/10.1038/482170a

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