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Drug discovery

Chemical beauty contest

Most drug candidates fail clinical trials, in many cases because the compounds have less than optimal physico-chemical properties. A new method for assessing the 'drug-likeness' of compounds might help to remedy the situation.

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Figure 1: Assessments of 'drug-likeness'.


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Correspondence to Paul Leeson.

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Leeson, P. Chemical beauty contest. Nature 481, 455–456 (2012).

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