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Cancer

A drug-resistant duo

The efficacy of the anticancer drug vemurafenib, which is used to treat metastatic melanoma, is plagued by acquired resistance. A picture of how such resistance develops is emerging. See Letter p.387

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Figure 1: The two faces of oncogenic B-RAF.

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Correspondence to Marc Therrien.

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Lavoie, H., Therrien, M. A drug-resistant duo. Nature 480, 329–330 (2011). https://doi.org/10.1038/480329a

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