Caspase-1 is one of the main culprits behind sepsis, a form of systemic inflammation. The related enzyme caspase-11 is also involved, but the relative roles of the two proteins have been confusing, until now. See Letter p.117
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Green, D. A heavyweight knocked out. Nature 479, 48–50 (2011). https://doi.org/10.1038/479048a
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DOI: https://doi.org/10.1038/479048a