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A heavyweight knocked out

Caspase-1 is one of the main culprits behind sepsis, a form of systemic inflammation. The related enzyme caspase-11 is also involved, but the relative roles of the two proteins have been confusing, until now. See Letter p.117

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Figure 1: Caspase-1 versus caspase-11.


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Correspondence to Douglas R. Green.

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Green, D. A heavyweight knocked out. Nature 479, 48–50 (2011).

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