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Molecular medicine

Defence against oxidative damage

Macular degeneration is a leading cause of blindness in the elderly in the developed world. Hope for prevention and treatment comes from the discovery of a protective mechanism against oxidative damage to the eye. See Letter p.76

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Figure 1: Mechanisms at work in age-related macular degeneration.


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Correspondence to Victor L. Perez.

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Cruz-Guilloty, F., Perez, V. Defence against oxidative damage. Nature 478, 42–43 (2011).

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