The mammalian immune system can fight a myriad of pathogens. In part, this involves a superfamily of cytoplasmic receptors that dictate assembly of specific pro-inflammatory inflammasome complexes. See Letters p.592 & p.596
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Monack, D. Recognition of a unique partner. Nature 477, 543–544 (2011). https://doi.org/10.1038/477543a
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DOI: https://doi.org/10.1038/477543a