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Cell division

Six degrees of separation

During cell division, the DNA-associated CENP-A protein recruits the kinetochore protein complex to assemble on chromosomes. A region of just six amino-acid residues earmarks CENP-A for this purpose. See Letter p.354

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Figure 1: Recognition of CENP-A-containing nucleosomes.

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Correspondence to Robin Allshire.

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Pidoux, A., Allshire, R. Six degrees of separation. Nature 477, 283–284 (2011). https://doi.org/10.1038/477283a

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