Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.


Weight loss through smoking


Many people smoke to keep their weight down. The identification of the molecular target in the brain for the appetite-suppressant effects of nicotine is a first step towards finding healthy alternatives to smoking for weight management.

Your institute does not have access to this article

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Figure 1: Appetite-suppressant effects of nicotine in the brain.


  1. Chiolero, A., Faeh, D., Paccaud, F. & Cornuz, J. Am. J. Clin. Nutr. 87, 801–809 (2008).

    CAS  Article  Google Scholar 


  3. Williamson, D. F. et al. N. Engl. J. Med. 324, 739–745 (1991).

    CAS  Article  Google Scholar 

  4. Mineur, Y. S. et al. Science 332, 1330–1332 (2011).

    ADS  CAS  Article  Google Scholar 

  5. Schwartz, M. W. et al. Nature 404, 661–671 (2000).

    CAS  Article  Google Scholar 

  6. Huang, H., Xu, Y. & van den Pol, A. J. Neurophysiol. doi:10.1152/jn.00740.2010 (2011).

  7. Greenfield, J. R. et al. N. Engl. J. Med. 360, 44–52 (2009).

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Randy J. Seeley.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Seeley, R., Sandoval, D. Weight loss through smoking. Nature 475, 176–177 (2011).

Download citation

  • Published:

  • Issue Date:

  • DOI:

Further reading


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing