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Structural biology

A platform for copper pumps

Copper is vital to most cells, but too much is lethal. The structure of a protein that pumps copper ions out of the cytosol provides insight into both the pumping mechanism and how certain mutations in the protein cause disease. See Article p.59

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Figure 1: A copper-exporting enzyme.

References

  1. Davies, K. Nature 361, 98 (1993).

    Article  ADS  CAS  Google Scholar 

  2. Gourdon, P. et al. Nature 475, 59–64 (2011).

    Article  CAS  Google Scholar 

  3. Banci, L. et al. Nature 465, 645–648 (2010).

    Article  ADS  CAS  Google Scholar 

  4. Setty, S. R. G. et al. Nature 454, 1142–1146 (2008).

    Article  ADS  CAS  Google Scholar 

  5. Kim, B.-E., Nevitt, T. & Thiele, D. J. Nature Chem. Biol. 4, 176–185 (2008).

    Article  CAS  Google Scholar 

  6. Abdel-Ghany, S. E., Müller-Moulé, P., Niyogi, K. K., Pilon, M. & Shikanai, T. Plant Cell 17, 1233–1251 (2005).

    Article  CAS  Google Scholar 

  7. White, C., Lee, J., Kambe, T., Fritsche, K. & Petris, M. J. J. Biol. Chem. 284, 33949–33956 (2009).

    Article  CAS  Google Scholar 

  8. González-Guerrero, M. & Argüello, J. M. Proc. Natl Acad. Sci. USA 105, 5992–5997 (2008).

    Article  ADS  Google Scholar 

  9. Su, C.-C. et al. Nature 470, 558–562 (2011).

    Article  ADS  CAS  Google Scholar 

  10. González-Guerrero, M., Raimunda, D., Cheng, X. & Argüello, J. M. Mol. Microbiol. 78, 1246–1258 (2010).

    Article  Google Scholar 

Download references

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Correspondence to Nigel J. Robinson.

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Robinson, N. A platform for copper pumps. Nature 475, 41–42 (2011). https://doi.org/10.1038/475041a

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