Nature crafts many molecules from common precursors, but this approach isn't always possible in chemical synthesis. A strategy for synthesizing a family of natural products succeeds by ignoring nature's blueprint. See Article p.461
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References
Snyder, S. A., Gollner, A. & Chiriac, M. I. Nature 474, 461–466 (2011).
Shenvi, R. A., O'Malley, D. P. & Baran, P. S. Acc. Chem. Res. 42, 530–541 (2009).
Feldman, K. S. & Lawlor, M. D. J. Am. Chem. Soc. 122, 7396–7397 (2000).
Ohmori, K., Shono, T., Hatakoshi, Y., Yano, T. & Suzuki, K. Angew. Chem. Int. Edn 50, 4862–4867 (2011).
Haslam, E. Practical Polyphenolics: From Structure to Molecular Recognition and Physiological Action (Cambridge Univ. Press, 1998).
Lin, M. & Yao, C.-S. in Studies in Natural Products Chemistry Vol. 33 (ed. Atta-ur-Rahman) 601–644 (Elsevier, 2006).
Nicolaou, K. C., Wu, T. R., Kang, Q. & Chen, D. Y.-K. Angew. Chem. Int. Edn 48, 3440–3443 (2009).
Snyder, S. A., Zografos, A. L. & Lin, Y. Angew. Chem. Int. Edn 46, 8186–8191 (2007).
Snyder, S. A., Breazzano, S. P., Ross, A. G., Lin, Y. & Zografos, A. L. J. Am. Chem. Soc. 131, 1753–1765 (2009).
Snyder, S. A. & Treitler, D. S. Angew. Chem. Int. Edn 48, 7899–7903 (2009).
Snyder, S. A., ElSohly, A. M. & Kontes, F. Nat. Prod. Rep. 28, 897–924 (2011).
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Quideau, S. Triumph for unnatural synthesis. Nature 474, 459–460 (2011). https://doi.org/10.1038/474459a
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DOI: https://doi.org/10.1038/474459a
