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Protein synthesis

Stop the nonsense

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A subtle biochemical alteration can reprogram signals that herald the termination of protein translation into signals encoding amino acids at the level of messenger RNA — and without altering the corresponding DNA. See Letter p.395

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Figure 1: Uridine and pseudouridine.

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Correspondence to Adrian R. Ferré-D'Amaré.

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Ferré-D'Amaré, A. Stop the nonsense. Nature 474, 289–290 (2011). https://doi.org/10.1038/474289a

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