A subtle biochemical alteration can reprogram signals that herald the termination of protein translation into signals encoding amino acids at the level of messenger RNA — and without altering the corresponding DNA. See Letter p.395
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Karijolich, J. & Yu, Y.-T. Nature 474, 395–398 (2011).
Murgola, E. J. in tRNA Structure, Biosynthesis, and Function (eds Söll, D. & RajBhandary, U. L.) 491–509 (ASM Press, 1995).
Weixlbaumer, A. et al. Science 322, 953–956 (2008).
Laurberg, M. et al. Nature 454, 852–857 (2008).
Charette, M. & Gray, M. W. IUBMB Life 49, 341–351 (2000).
Hamma, T. & Ferré-D'Amaré, A. R. Chem. Biol. 13, 1125–1135 (2006).
Hamma, T. & Ferré-D'Amaré, A. R. J. Biol. Chem. 285, 805–809 (2010).
Frischmeyer, P. A. & Dietz, H. C. Hum. Mol. Genet. 8, 1893–1900 (1999).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Ferré-D'Amaré, A. Stop the nonsense. Nature 474, 289–290 (2011). https://doi.org/10.1038/474289a
Published:
Issue Date:
DOI: https://doi.org/10.1038/474289a