Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

DNA repair

Cyclin D1 multitasks

Cyclin D1 is one of the drivers of the cell cycle, and its deregulation may promote the development of tumours. Surprisingly, this protein also mediates the repair of damaged DNA, a mechanism that commonly prevents cancer. See Letter p.230

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Dual role of cyclin D1.

References

  1. Jackson, S. P. & Bartek, J. Nature 461, 1071–1078 (2009).

    Article  ADS  CAS  Google Scholar 

  2. Sherr, C. J. & Roberts, J. M. Genes Dev. 18, 2699–2711 (2004).

    Article  CAS  Google Scholar 

  3. Jirawatnotai, S. et al. Nature 474, 230–234 (2011).

    Article  CAS  Google Scholar 

  4. Mazón, G., Mimitou, E. P. & Symington, L. S. Cell 142, 646 (2010).

    Article  Google Scholar 

  5. Bartek, J. et al. Curr. Opin. Cell Biol. 8, 805–814 (1996).

    Article  CAS  Google Scholar 

  6. Jensen, R. B., Carreira, A. & Kowalczykowski, S. C. Nature 467, 678–683 (2010).

    Article  ADS  CAS  Google Scholar 

  7. Thorslund, T. et al. Nature Struct. Mol. Biol. 17, 1263–1265 (2010).

    Article  CAS  Google Scholar 

  8. Hoeijmakers, J. H. J. Nature 411, 366–374 (2001).

    Article  ADS  CAS  Google Scholar 

  9. Halazonetis, T. et al. Science 319, 1352–1355 (2008).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Jiri Bartek or Jiri Lukas.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Bartek, J., Lukas, J. Cyclin D1 multitasks. Nature 474, 171–172 (2011). https://doi.org/10.1038/474171a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/474171a

This article is cited by

Search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer