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Immunology

In command of commensals

Humans must maintain a balanced composition for the trillions of commensal microbes that inhabit their gut, but how they do this is largely unclear. It now emerges that one factor is a molecular pathway in gut epithelial cells.

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Figure 1: The NLRP6 inflammasome — a guardian of intestinal homeostasis.

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Correspondence to Menno van Lookeren Campagne or Vishva M. Dixit.

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M.v.L.C. and V.M.D. are employees of Genentech Inc., a for-profit institution.

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van Lookeren Campagne, M., Dixit, V. In command of commensals. Nature 474, 42–43 (2011). https://doi.org/10.1038/474042a

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