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Neuroscience

Sleepy neurons?

A study in rats suggests that individual neurons take a nap when the brain is forced to stay awake, and that the basic unit of sleep is the electrical activity of single cortical neurons. See Article p.443

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Figure 1: Neuronal activity in the rat brain.

References

  1. Altena, E. et al. Prog. Brain Res. 185, 181–205 (2010).

    Article  Google Scholar 

  2. Bloom, H. G. et al. J. Am. Geriatr. Soc. 57, 761–789 (2009).

    Article  Google Scholar 

  3. Zeitzer, J. M., Nishino, S. & Mignot, E. Trends Pharmacol. Sci. 27, 368–374 (2006).

    CAS  Article  Google Scholar 

  4. Saper, C. B. et al. Neuron 68, 1023–1042 (2010).

    CAS  Article  Google Scholar 

  5. Crocker, A. & Sehgal, A. Genes Dev. 24, 1220–1235 (2010).

    CAS  Article  Google Scholar 

  6. Vyazovskiy, V. V. et al. Nature 472, 443–447 (2011).

    ADS  CAS  Article  Google Scholar 

  7. Steriade, M. Neuroscience 137, 1087–1106 (2006).

    CAS  Article  Google Scholar 

  8. McCormick, D. A. Curr. Biol. 15, R294–R296 (2005).

    CAS  Article  Google Scholar 

  9. Vyazovskiy, V. V. et al. Neuron 63, 865–878 (2009).

    CAS  Article  Google Scholar 

  10. Schiffelholz, T. & Aldenhoff, J. B. Neurosci. Lett. 328, 41–44 (2002).

    CAS  Article  Google Scholar 

  11. Dijk, D. J. & Czeisler, C. A. J. Neurosci. 15, 3526–3538 (1995).

    CAS  Article  Google Scholar 

  12. Krueger, J. M. et al. Nature Rev. Neurosci. 9, 910–919 (2008).

    CAS  Article  Google Scholar 

  13. Rector, D. M., Topchiy, I. & Rojas, M. Sleep 28, A26 (2005).

    Google Scholar 

  14. Hanlon, E. C. et al. Sleep 32, 719–729 (2009).

    Article  Google Scholar 

  15. Mahowald, M. W. & Schenck, C. H. Nature 437, 1279–1285 (2005).

    ADS  CAS  Article  Google Scholar 

  16. Siegel, J. M. Nature 437, 1264–1271 (2005).

    ADS  CAS  Article  Google Scholar 

  17. Rioult-Pedotti, M.-S., Friedman, D. & Donoghue, J. P. Science 290, 533–536 (2000).

    ADS  CAS  Article  Google Scholar 

Download references

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Correspondence to Christopher S. Colwell.

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Colwell, C. Sleepy neurons?. Nature 472, 427–428 (2011). https://doi.org/10.1038/472427a

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