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Host–microbe interaction

Innate immunity cues virulence

Nature volume 472, pages 179–180 (2011)Cite this article

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Salmonella intestinal pathogens employ a clever trick. They use the immune response that their host triggers to destroy them to enhance the expression of genes that mediate the pathogens' virulence.

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Figure 1: Salmonella and its effect on macrophages.

References

  1. Arpaia, N. et al. Cell 144, 675–688 (2011).

    Article  CAS  Google Scholar 

  2. Haraga, A., Ohlson, M. B. & Miller, S. I. Nature Rev. Microbiol. 6, 53–66 (2008).

    Article  CAS  Google Scholar 

  3. Yamamoto, M. & Takeda, K. Gastroenterol. Res. Pract. 2010, 240365 (2010).

    Article  Google Scholar 

  4. Shea, J. E., Hensel, M., Gleeson, C. & Holden, D. W. Proc. Natl Acad. Sci. USA 93, 2593–2597 (1996).

    Article  ADS  CAS  Google Scholar 

  5. Silphaduang, U., Mascarenhas, M., Karmali, M. & Coombes, B. K. J. Bacteriol. 189, 3669–3673 (2007).

    Article  CAS  Google Scholar 

  6. Yu, X.-J., McGourty, K., Liu, M., Unsworth, K. E. & Holden, D. W. Science 328, 1040–1043 (2010).

    Article  ADS  CAS  Google Scholar 

  7. Le Negrate, G. et al. J. Immunol. 180, 5045–5056 (2008).

    Article  CAS  Google Scholar 

  8. Woodward, J. J., Iavarone, A. T. & Portnoy, D. A. Science 328, 1703–1705 (2010).

    Article  ADS  CAS  Google Scholar 

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Authors and Affiliations

  1. Michelle M. C. Buckner and B. Brett Finlay are in the Department of Microbiology and Immunology, and at the Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.,

    Michelle M. C. Buckner & B. Brett Finlay

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  1. Michelle M. C. Buckner
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  2. B. Brett Finlay
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Correspondence to B. Brett Finlay.

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Buckner, M., Finlay, B. Innate immunity cues virulence. Nature 472, 179–180 (2011). https://doi.org/10.1038/472179a

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