Anticancer therapies can impair male fertility. Whereas men can opt to freeze their sperm before treatment, young boys don't produce mature sperm and so lack this choice. Work in mice offers hope for such patients. See Letter p.504
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Sato, T. et al. Nature 471, 504–507 (2011).
Russell, L. D., Ettlin, R. A., Hikim, A. P. S. & Clegg, E. D. Histological and Histopathological Evaluation of the Testis (Cache River Press, 1990).
Staub, C. J. Androl. 22, 911–926 (2001).
Gohbara, A. et al. Biol. Reprod. 83, 261–267 (2010).
Price, P. J., Goldsborough, M. D. & Tilkins, M. L. International patent application: PCT/US98/00467 (1998).
Brinster, R. L. & Zimmermann, J. W. Proc. Natl Acad. Sci. USA 91, 11298–11302 (1994).
Kee, K., Angeles, V. T., Flores, M., Nguyen, H. N. & Reijo Pera, R. A. Nature 462, 222–225 (2009).
Nayernia, K. et al. Dev. Cell 11, 125–132 (2006).
Author information
Authors and Affiliations
Corresponding authors
Rights and permissions
About this article
Cite this article
Seandel, M., Rafii, S. In vitro sperm maturation. Nature 471, 453–454 (2011). https://doi.org/10.1038/471453a
Published:
Issue Date:
DOI: https://doi.org/10.1038/471453a