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Prion diseases

Infectivity versus toxicity

Prions are infectious proteins that can cause deadly diseases in mammals. Detailed measurements of infectivity suggest that there may be distinct infectious and toxic versions of this protein. See Letter p.540

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Figure 1: Does PrP protein concentration matter?


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Correspondence to Reed B. Wickner.

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Wickner, R. Infectivity versus toxicity. Nature 470, 470–471 (2011).

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