Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Cognitive enhancement

A molecular memory booster

For many – if not all – of us, cognitive enhancement is desirable, but agents that would truly improve memory are hard to find. Unexpectedly, the product of an imprinted gene emerges as a promising candidate. See Article p.491

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1: IGF-II can promote memory retention.

References

  1. Maher, B. Nature 452, 674–675 (2008).

    Article  ADS  CAS  Google Scholar 

  2. Chen, D. Y. et al. Nature 469, 491–497 (2011).

    Article  ADS  CAS  Google Scholar 

  3. Russo, V. C. et al. Endocr. Rev. 26, 916–943 (2005).

    Article  CAS  Google Scholar 

  4. Sonntag, W. E. et al. Neuroscience 88, 269–279 (1999).

    Article  CAS  Google Scholar 

  5. Dudai, Y. Annu. Rev. Psychol. 55, 51–86 (2004).

    Article  Google Scholar 

  6. Milekic, M. H. & Alberini, C. M. Neuron 36, 521–525 (2002).

    Article  CAS  Google Scholar 

  7. Feinberg, A. P. Nature 447, 433–440 (2007).

    Article  ADS  CAS  Google Scholar 

  8. Reik, W. & Walter, J. Nature Rev. Genet. 2, 21–32 (2001).

    Article  CAS  Google Scholar 

  9. Gregg, C. et al. Science 329, 643–648 (2010).

    Article  ADS  CAS  Google Scholar 

  10. Day, J. J. & Sweatt, J. D. Nature Neurosci. 13, 1319–1323 (2010).

    Article  CAS  Google Scholar 

  11. Fischer, A., Sananbenesi, F., Wang, X., Dobbin, M. & Tsai, L.-H. Nature 447, 178–182 (2007).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gräff, J., Tsai, LH. A molecular memory booster. Nature 469, 474–475 (2011). https://doi.org/10.1038/469474a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/469474a

This article is cited by

Search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research