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Structural biology

An alphavirus puzzle solved

Alphaviruses infect their host by binding to cellular receptors and fusing with cell membranes. New studies define the receptor-binding protein of these viruses and its regulation of the membrane-fusion reaction. See Letters p.705 & p.709

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Figure 1: The alphavirus infection cycle.

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Kielian, M. An alphavirus puzzle solved. Nature 468, 645–646 (2010). https://doi.org/10.1038/468645a

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