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Stem cells

The blood balance

Blood cells are generated from haematopoietic stem cells on demand. The protein Lkb1, which lies at the crossroad of energy metabolism and cell growth, seems to regulate these stem cells' dynamics. See Articles p.653, p.659 & Letter p.701

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Figure 1: The regulatory role of Lkb1.


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Competing interests

L.I.Z. is a founder and shareholder of Fate Therapeutics, and a scientific adviser for Stemgent.

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Durand, E., Zon, L. The blood balance. Nature 468, 644–645 (2010).

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