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Neuroscience

Excessive mobility interrupted

Mobile DNA sequences called L1 contribute to the brain's genetic heterogeneity and may affect neuron function. The protein MeCP2, which is mutated in Rett syndrome, seems to regulate the activity of these genomic elements. See Letter p.443

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Figure 1: Regulation of L1 expression.

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Studer, L. Excessive mobility interrupted. Nature 468, 383–384 (2010). https://doi.org/10.1038/468383a

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