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Structural biology

On stress and pressure

The protein angiotensinogen must undergo conformational changes to be cleaved into a precursor of the hormone angiotensin, which increases blood pressure. Oxidative stress seems to mediate this structural alteration. See Letter p.108

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Figure 1: The renin–angiotensin system.


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Sigmund, C. On stress and pressure. Nature 468, 46–47 (2010).

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