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Structural biology

On stress and pressure

Nature volume 468, pages 46–47 (2010)Cite this article

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The protein angiotensinogen must undergo conformational changes to be cleaved into a precursor of the hormone angiotensin, which increases blood pressure. Oxidative stress seems to mediate this structural alteration. See Letter p.108

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Figure 1: The renin–angiotensin system.

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  1. Curt D. Sigmund is in the Department of Pharmacology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA. curt-sigmund@uiowa.edu,

    Curt D. Sigmund

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  1. Curt D. Sigmund
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Sigmund, C. On stress and pressure. Nature 468, 46–47 (2010). https://doi.org/10.1038/468046a

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