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Metabolic disorders

Fathers' nutritional legacy

A female can develop a diabetes-like disease due to a high fat content in her father's diet before she was conceived. Epigenetic modifications of the father's sperm DNA might underlie this peculiar observation. See Letter p.963

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Figure 1: Environmental effects across generations.


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Skinner, M. Fathers' nutritional legacy. Nature 467, 922–923 (2010).

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