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Biological imaging

Beyond fluorescence

Nature volume 467, pages 407–408 (2010)Cite this article

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Nanoparticles that generate light through a mechanism known as second harmonic generation have been used to image live tissue. The particles overcome many problems associated with fluorescent probes for bioimaging.

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Figure 1: One photon or two?

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Authors and Affiliations

  1. Bruce E. Cohen is at the Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA. becohen@lbl.gov ,

    Bruce E. Cohen

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  1. Bruce E. Cohen
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Cohen, B. Beyond fluorescence. Nature 467, 407–408 (2010). https://doi.org/10.1038/467407a

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