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Gene targeting

Enter the rat

Advances in stem-cell technology have broken the barrier to gene targeting in mammals other than mice. A wide array of research opportunities now opens up, especially in studies involving the laboratory rat.

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Figure 1: Approaches to gene targeting in rats2,3,4.

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Hamra, F. Enter the rat. Nature 467, 161–163 (2010). https://doi.org/10.1038/467161a

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