Stem cells can renew themselves indefinitely — a feature that is often attributed to asymmetrical cell division. Fresh experimental and mathematical models of the intestine provide evidence that begs to differ.
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Verzi, M., Shivdasani, R. The intestinal–crypt casino. Nature 467, 1055–1056 (2010). https://doi.org/10.1038/4671055a
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DOI: https://doi.org/10.1038/4671055a
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A calibrated agent-based computer model of stochastic cell dynamics in normal human colon crypts useful for in silico experiments
Theoretical Biology and Medical Modelling (2013)