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Cancer

Genomic evolution of metastasis

Prognosis for patients with pancreatic cancer is bleak, often owing to late diagnosis. The estimate that at least 15 years pass from tumour initiation to malignancy offers hope for early detection and prevention. See Letters p.1109 & p.1114

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Figure 1: The pancreatic-cancer timeline.

References

  1. Campbell, P. J. et al. Nature 467, 1109–1113 (2010).

    ADS  CAS  Article  Google Scholar 

  2. Yachida, S. et al. Nature 467, 1114–1117 (2010).

    ADS  CAS  Article  Google Scholar 

  3. McClintock, B. Genetics 26, 234–282 (1941).

    CAS  PubMed  PubMed Central  Google Scholar 

  4. Lo, A. W. I. et al. Neoplasia 4, 531–538 (2002).

    CAS  Article  Google Scholar 

  5. Meza, R., Jeon, J., Moolgavkar, S. H. & Luebeck, E. G. Proc. Natl Acad. Sci. USA 105, 16284–16289 (2008).

    ADS  CAS  Article  Google Scholar 

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Luebeck, E. Genomic evolution of metastasis. Nature 467, 1053–1055 (2010). https://doi.org/10.1038/4671053a

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